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Epithelial ovarian cancer definition, symptoms and treatment


Epithelial ovarian cancer or ovarian cancer is known as derived from epithelial cells account for 90% of all cases of ovarian cancer. Ovarian cancer is the leading cause of death for the 5th largest in the United States and is one of the seven most common malignancies worldwide. Ovarian cancer has a high mortality rate, of the 23,100 new cases of ovarian cancer, approximately half of the 14,000 or more women die from this disease. Epithelial ovarian cancer is rarely found in women aged <40 years. The peak occurred in women aged 60-64 years. The incidence of epithelial ovarian cancer is lower in developing countries and Japan.

As many as 60% of women diagnosed with ovarian cancer has entered the advanced stage of the disease. In general, you do not get early symptoms of these cancers, if there are usually vague. These symptoms including pelvic pain, bloating, fatigue, weight loss, constipation (constipation), irregular menstrual bleeding. On physical examination found the existence of a mass or lump in the pelvis is a sign of the suspect.

Detection and Prevention

  •      The criteria for an effective screening

Until now there is no tool that can effectively and efficiently in the early detection of ovarian cancer

  •      Routine pelvic examinations per year. This examination is used fatherly detect early ovarian cancer but do not have a high sensitivity
  •      Cancer antigen 125 (CA-125). The antigen is expressed by 80% of epithelial ovarian cancer nonmusinous. Levels higher than 35 U / ml is abnormal
  •      Transvaginal ultrasonography. This tool is considered for a screening tool combined with Doppler examination
  •      Prevention. If a woman’s pelvic surgery, then the decision will prevent the ovaries as well as the risk of ovarian cancer forever. But keep in mind the risks of premature and will premenopausal osteoporosis and heart disease that can result from removal of the ovaries. In addition it is also recommended the use of the contraceptive pill

Examination Support

Ultrasonography (USG) can clarify this disease

Therapy

Therapy of ovarian cancer depends on the stage of the disease, type of disease (primary or recurrent <kambuh kembali>), treatment options, and body condition.

  • Ovarian Cancer atypical

This atypical cancers have different properties than other types of ovarian cancer is malignant. Commonly found in women age 40 years (malignancy at the age of 60 years). 20% of early stage can spread to intra-abdominal (stomach) and require surgical treatment. Cancer patients with early-stage ovarian atypical who still want to preserve their fertility can make unilateral salpingo-oophorectomi (surgical removal of the ovaries that contain cancer)

  • Early-stage ovarian cancer

Early-stage ovarian cancers were stage I and II. The therapy can be done at this stage is surgery (total abdominal hysterectomy, bilateral salpingo-oophorektomi), chemotherapy (in the case of the low success rate, given after surgery), and radiation

Advanced-stage ovarian cancer

This stage is always in need of optimal surgical treatment followed by chemotherapy after surgery to improve survival. Radiation around the abdomen (whole abdominal radiation) may be an alternative to chemotherapy

  •      Relapsed ovarian cancer

Patients with recurrent ovarian cancer who are candidates for surgery a second time with chemotherapy using a different agent. Hormonal therapy may also be used. The therapy is still in the research of stem cell therapy, immunotherapy using interferon, and genetic therapies